PARP-1 Terminal Antibody
Inventor: William Kraus
Category: Biotech Research & Production Tools
Polyclonal antibodies against the N-terminal of PARP-1, Poly [ADP-ribose] polymerase 1, a chromatin-associated enzyme that modifies various nuclear proteins. The modification is dependent on DNA and is involved in the regulation of various important cellular processes. This PARP-1 terminal antibody has been validated for use in Western blotting, chromatin IP, and reported to work in immunohistochemistry and immunoprecipitation.
View PDFRas Activation Assay
Inventor: David Shalloway
Category: Biotech Research & Production Tools
The Ras switch operates by alternating between an active, GTP-bound state and an inactive, GDP-bound state. The assay provides a simple means of quantitating Ras activation in cells. The amount of activated Ras is determined by a western blot using a Ras specific antibody. The assay can be used in research or drug discovery, and also may have applications in detecting cancer.
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