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Learn about products currently on the market based on Cornell-licensed technologies.

Products

3,5-difluoro-4-hydroxybenzylidene imidazolinone

Category: Biotech Research & Production Tools
Department: Pharmacology
Inventor: Samie Jaffrey

3,5-difluoro-4-hydroxybenzylidene imidazolinone (DFHBI) is a small molecule fluorophore. Upon binding to its aptamer, this molecule exhibits the spectral properties of enhanced green fluorescent protein (EGFP).

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Anti-pro-BDNF Antibody

Category: Biotech Research & Production Tools
Department: Hematology & Medical Oncology
Inventor: Barbara Hempstead

Pro-BDNF is the uncleaved precursor form of BDNF. The anti-pro-BDNF antibody was generated by using GST-fusion protein with a peptide of BDNF as the immunogen in chickens. The antibody detects pro-BDNF, but not mature BDNF.

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Anti-pro-NGF Antibody

Category: Biotech Research & Production Tools
Department: Hematology & Medical Oncology
Inventor: Barbara Hempstead

Pro-NGF is the uncleaved precursor form of NGF. The anti-pro-NGF antibody was generated by using GST-fusion protein with a peptide of NGF as the immunogen in rabbits. Unlike other antibodies generated to the mature domain of NGF, this antibody detects pro-NGF, but not mature NGF.

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Antibody to mouse CD36

Category: Biotech Research & Production Tools
Department: Medicine
Inventor: Maria Febbraio, Roy Silverstein

CD36 is a cell surface class B scavenger receptor. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It may function as a cell adhesion molecule.

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Champion™ pET SUMO Expression System

Category: Biotech Research & Production Tools
Department: Medical Sciences
Inventor: Christopher Lima

The Champion™ pET SUMO Protein Expression System offers a new and important tool for high-level soluble expression of proteins and peptides with native n-termini. The companion SUMO Protease enzyme works with the great specificity and efficiency on most substrates in a wide range of temperatures without undue damage to the protein of interest.

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Cyclopure

Category: Device
Department: Chemistry & Chemical Biology
Inventor: William R. Dichtel

A first-ever filter that brings PFAS protection to your countertop.

Digycyl-Lysine Antibody, clone GX41

Category: Biotech Research & Production Tools
Department: Pharmacology
Inventor: Samie Jaffrey

This is a monoclonal antibody which recognizes a diglycine modified lysine, the trypsinized remnant of ubiquitination. The recognition does not depend on neighboring backbone amino acid sequences. It has been shown to specifically detect peptides derived from the ubiquitinated portion of proteins.

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Electron Microscope PixelArray Detector

Category: Hardware
Department: Physics
Inventor: Sol M. Gruner

High dynamic range direct electron detector for 4D STEM application.

Exotanium

Category: Software
Department: Computer Science
Inventor: Hakim Weatherspoon

Exotanium offers simple-to-use products that allow organizations who rely heavily on cloud computing to reduce their costs by half or more, while ensuring the same extraordinary quality of service.

Haikubox

Category: Device
Department: Laboratory of Ornithology
Inventor: Holger Klinck

Haikubox listens for birdsong and uses a proprietary neural network to identify and report bird species.

High Pressure Cryo-Cooler™

Category: Biotech Research & Production Tools
Department: Physics
Inventor: Sol Gruner

HPC-201 cryocooling was developed as an alternative method for cryopreservation of macromolecular crystals.

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IDEXX BVDV PI X2 Test

Category: Diagnostics
Department: Population Medicine and Diagnostic Services
Inventor: Edward Dubovi

The IDEXX BVDV PI X2 Test is the only USDA-licensed test for detecting persistently infected (PI) calves. The kit offers superior sensitivity, speed, and simplicity compared to other test methods. It comes with easy to use, highly stable reagents resistant to temperature fluctuations.

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Immortalized Mouse Cardiac Endothelial Cell (MCEC) Line

Category: Biotech Research & Production Tools
Department: Medicine
Inventor: Babette Weksler

Immortalized Mouse Cardiac Endothelial Cell (MCEC) Line provides an excellent in vitro model for evaluation of the effects of specific genetic additions or deletions on endothelial physiology, because these cells can be easily and stably transfected with different genes or interest.

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ISCAlure-Tuta

Category: AgTech
Department: Chemistry and Chemical Biology
Inventor: Athula Attygalle

ISCAlure-Tuta is a pheromone-based lure product for South American tomato leafminer, Tuta absoluta, that attracts and traps the insect. The lure is loaded into a lure dispenser to protect the pheromone compounds from the elements and modulate the release of the pheromone with a release rate mimicking that of the leafminer.

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JK1 Passage-Independent Feeder Cells

Category: Biotech Research & Production Tools
Department: Cell & Developmental Biology
Inventor: Marco Seandel, Shahin Rafii

JK1 is capable of promoting long term culture of primitive cells, allowing for the identification of stromal derived factors that support long term proliferation of various types of stem cells. This line can be passaged serially without losing its capacity to support stem cell self renewal and survival, making it a convenient alternative to other types of feeder layers.

LabcliQ

Category: Software
Department: Environmental Health & Safety Administration
Inventor:

LabcliQ, is an online program for workow and inspections for environmental health and safety
departments.

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Lavender Foal Syndrome Test

Category: Diagnostics
Department: Animal Science
Inventor: Douglas Antczak, Samantha Brooks

Testing is easy and highly accurate, and can be performed at any point in time in the life of the animal with pulled hair, whole blood, in EDTA or bristle style cheek swaps. All breeding animals should be tested to avoid major losses and heartache for owners and to prevent morbidity in the animals.

Leopard Complex & Congenital Stationary Night Blindness Test

Category: Diagnostics
Department: Animal Science
Inventor: Samantha Brooks

The genetic basis for Leopard Complex has been identified and this test can determine the specific mutation. Large insertion within the gene known as TRPM1 is the mutation responsible for LP.

Light Lace™

Category: Device
Department: Mechanical and Aerospace Engineering
Inventor: Robert F. Shepherd

Through light, Light Lace™ measures muscle fatigue, respiration and motion. All at the speed of light.

LSM 7 MP and LSM 710 NLO

Category: Semiconductor
Department: Applied and Engineering Physics
Inventor: Chris Xu, Watt Webb

A laser scanning microscope produces molecular excitation in a sample by simultaneous absorption of two or more photons thereby providing three-dimensional resolution

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Messenger®; and Employ®

Category: AgTech
Department: Plant Pathology & Plant-Microbe Biology (SIPS)
Inventor: Steven Beer

Product series for foliar spray that reduces transplant shock, enhances crop growth quality and yield, increases plant stamina and vigor and suppresses nematode egg production. They are used on vegetables, flowers, turf, trees, and landscape plants.

MicroMountsTM

Category: BioTech research
Department: Physics
Inventor: Robert Thorne

MicroMounts™ are the highest performance tools for manipulating and mounting protein crystals, virus crystals, and small molecule/inorganic crystals, as well as, a wide range of other small, fragile samples.

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MicroTools

Category: BioTech research
Department: Physics
Inventor: Robert Thorne

MicroTools™ are designed for use with protein crystals, single cells, and other small samples from a few micrometers to a millimeter in size.

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NIAGEN®

Category: Therapeutics
Department: Medicine
Inventor: Non-disclosed

NIAGEN®, ChromaDex’s commercial brand of NR has been clinically demonstrated to significantly increase NAD+ and to promote mitochondria health, healthy cellular metabolism and healthy aging.

Nobivac®; Canine Flu H3N8

Category: Therapeutics
Department: Population Medicine and Diagnostic Services
Inventor: Edward Dubovi

NOBIVAC® CANINE FLU H3N8 PROVIDES INFLUENZA PROTECTION FOR DOGS

Canine Influenza (H3N8) Virus (inactivated virus). Demonstrated to reduce incidence and severity of lung lesions, as well as duration of coughing and viral shedding. (https://www.merck-animal-health-usa.com/nobivac/nobivac-canine-flu-h3n8)

 

OptiPhos®

Category: AgTech
Department: Animal Science
Inventor: Xingen Lei

OptiPhos® releases more phosphorous from feed grain in poultry and swine than any other phytase product. This results in an enhanced diet for the animal as inorganic phosphate is replaced by energy. In addition, OptiPhos® benefits the environment as substantially less phosphorus is released onto the land. This product was approved by the FDA in 2005.

PacBio RS

Category: BioTech research
Department: Applied and Engineering Physics
Inventor: Harold Craighead

The PacBio RS sequencing technology resolves single molecules in real time, allowing observation of structural and cell type variation not accessible with other technologies.

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PARP-1 Terminal Antibody

Category: Biotech Research & Production Tools
Department: Molecular Biology and Genetics
Inventor: William Kraus

Polyclonal antibodies against the N-terminal of PARP-1, Poly [ADP-ribose] polymerase 1, a chromatin-associated enzyme that modifies various nuclear proteins. The modification is dependent on DNA and is involved in the regulation of various important cellular processes. This PARP-1 terminal antibody has been validated for use in Western blotting, chromatin IP, and reported to work in immunohistochemistry and immunoprecipitation.

prcd-PRA Test

Category: Diagnostics
Department: Baker Institute for Animal Health
Inventor: Gregory Acland

Progressive Retinal Atrophy (PRA) is a heterogeneous class of retinal disorders that share a broadly similar clinical disease phenotype. The prcd-PRA test is done on a small sample of blood from the dog. The test analyzes the specific DNA mutation causing the prcd-PRA. The test detects the mutant, abnormal gene copy and the normal gene copy. The result of the test is a genotype and allows separation of dogs into three groups: Normal/Clear (homozygous normal), Carrier (heterozygous), and Affected (homozygous mutant).

ProAct™

Category: AgTech
Department: Plant Pathology & Plant-Microbe Biology (SIPS)
Inventor: Alan Collmer

ProAct™ is a foliar spray product for reducing nematode populations, improving overall plant health and yield. ProAct™ is the only foliar spray product labeled for use against nematodes in corn and soybeans.

Ras Activation Assay

Category: Biotech Research & Production Tools
Department: Molecular Biology and Genetics
Inventor: David Shalloway

The Ras switch operates by alternating between an active, GTP-bound state and an inactive, GDP-bound state. The assay provides a simple means of quantitating Ras activation in cells. The amount of activated Ras is determined by a western blot using a Ras specific antibody. The assay can be used in research or drug discovery, and also may have applications in detecting cancer.

RD/OSD Test

Category: Diagnostics
Department: Baker Institute for Animal Health
Inventor: Gregory Acland

The Inherited Retinal Dysplasia (RD)/OculoSkeletal Dysplasia (OSD) test is done on a small sample of blood obtained by a veterinarian or on a cheek swab. The test will identify dogs as being Normal, Carrier, or Affected with OSD. It is expected that many, but not all, carriers will show significant retinal dysplasia-retinal folding.

ReproCHEK™; Canine Pregnancy Test

Category: Diagnostics
Department: Microbiology and Immunology
Inventor: George Lust

ReproCHEK™ Canine Pregnancy Test Kit uses highly purified and specific antibodies to detect the presence of the hormon relaxin in canine whole blood or plasma. The presence of significant amounts of relaxin indicates pregnancy. ReproCHEK™ offers an early, inexpensive, and reliable means of determining canine pregnancy.

RootShield®

Category: AgTech
Department: Horticultural Sciences
Inventor: Gary Harman

A biological fungicide labeled for organic use in production that prevents a broad spectrum of root diseases using the highly-effective hybrid fungus Trichoderma harzianum.

SabrEx™ for Corn

Category: AgTech
Department: Horticultural Sciences
Inventor: Gary Harman

SabrEx™ for Corn has been shown to create more robust root systems, induce resistance to plant stresses like dry weather or disease, and increase water and nutrient efficiency. SabrEx™ for Corn contains a unique patented strain of the beneficial fungus Trichoderma harzianum that works on most hybrids of corn and grows with the root system of the plant, to help it grow larger, stronger, and more resistant to disease.

SabrEx™ for Wheat

Category: AgTech
Department: Horticultural Sciences
Inventor: Gary Harman

SabrEx™ for Wheat is a line of proven seed treatments for field crops. It boosts tillering in wheat crops to create more plants and a more robust root system to absorb and carry more nutrients to the plant. The result is a healthier, sturdier plant that resists lodging and becomes easier to harvest.