Department: Hematology & Medical Oncology
Inventor: Barbara Hempstead
Pro-NGF is the uncleaved precursor form of NGF. The anti-pro-NGF antibody was generated by using GST-fusion protein with a peptide of NGF as the immunogen in rabbits. Unlike other antibodies generated to the mature domain of NGF, this antibody detects pro-NGF, but not mature NGF.